سخنرانی دکتر رادفر در سمینار علمی بازآموزی استان اصفهان

انواع مکمل ها و تداخالت آنها

دکتر محمد رادفر
دکترای عمومی داروسازی
متخصص تغذیه و رژیم درمانی
عضو انجمن تغذیه و انجمن داروسازان ایران
تابستان 1398

:Indications

Iodine is used to prevent iodine deficiency and its consequences, including goiter.
It is also used for treating a skin disease caused by a fungus (cutaneous
sporotrichosis); treating fibrocystic breast disease; preventing breast cancer, eye
isease, diabetes, heart disease , stroke, and as an expectorant.

Side effects

Common side effects include nausea and stomach pain, runny nose, headache,
metallic taste, and diarrhea.
In sensitive people, iodine can cause side effects including swelling of the lips and
face (angioedema), severe bleeding and bruising, fever, joint pain, lymph node
enlargement, allergic reactions including hives, and death.

:Dosing

The National Institute of Medicine has set Adequate Intake (AI) of iodine for
infants: 0 to 6 months, 110 mcg/day; 7 to 12 months, 130 mcg/day.
For children and adults, Recommended Dietary Amounts (RDA) have been set:
children 1 to 8 years, 90 mcg/day; 9 to 13 years, 120 mcg/day; people age 14 and
older, 150 mcg/day. For pregnant women, the RDA is 209 mcg/day, and
breastfeeding women, 290 mcg/day.
Tolerable Upper Intake Levels (UL), the highest level of intake that is not likely to
cause unwanted side effects, for iodine intake have been set: children 1 to 3 years,
200 mcg/day; 4 to 8 years, 300 mcg/day; 9 to 13 years, 600 mcg/day; 14 to 18 years
(including pregnancy and breastfeeding), 900 mcg/day. For adults older than age 19
including pregnant and breastfeeding women, the Tolerable Upper Intake Level is
1100 mcg/day.

:Deficiency

• Iodine deficiency during pregnancy is serious for both the mother and the baby. It
can lead to high blood pressure during pregnancy for the mother, and mental
retardation for the baby. Iodine plays an important role in development of the
central nervous system.
• Iodine deficiency and the resulting low levels of thyroid hormone can cause
women to stop ovulating, leading to infertility (treatment of borderline
hypothyroidism for fertility). Iodine deficiency can also lead to an autoimmune
disease of the thyroid and may increase the risk of getting thyroid cancer. Some
researchers think that iodine deficiency might also increase the risk of other
cancers such as prostate, breast, endometrial, and ovarian cancer.

:Drug interactions

Medications for an overactive thyroid (Antithyroid drugs) interacts with
IODINE
Iodine supplements interact with overactive thyroid medications
Some of these medications include methenamine mandelate, methimazole
(Tapazole), potassium iodide (Thyro-Block)

…

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